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Topamax is the only medicine that works for me, I am willing to live with the side effects to keep from going up and down. The worst side effect for me has been trouble comprehending, and mild memory loss. When I lowered the dose from 400 to 100 I don't have comprehending or memory problems now. The great part about Topamax is weight loss, and not gaining weight.



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Absorption of Topiramate is rapid, with peak plasma concentrations occurring at approximately 2 hours following a 400 mg oral dose.

An anticonvulsant medication FDA-approved for use alone or with other medications to treat patients with epilepsy who have certain types of seizures.

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Sachs G, Koslow GC, Orsini C, Cosgrove V, Sambur M, Demopulos C, Ghaemi S: Topiramate shows efficacy in the treatment of refractory bipolar mood disorder.

Your healthcare provider should check your heart rate while you take Qsymia.

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Bowden CL, Calabrese JR, McElroy SL, Gyulai L, Wassef A, Petty F, Pope HG, Chou JC, Keck PE, Rhodes LJ, Swann AC, Hirschfeld RM, Wozniak PJ: A randomised placebo-controlled 12 months trial of divalproex and lithium in treatment of outpatients with bipolar I disorder.

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After 1 and 2 years, the randomized trial revealed no significant differences in outcome between groups, whereas, in the observational cohort clinically and statistically significant differences in improvement were reported for patients who had surgery.

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Antiepileptic drugs (AEDs), including topiramate capsules (sprinkle), increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication.

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My neurologist put me on gabapentin for a while, but my pcp took me off that and put me on because gaba causes weight gain, which I certainly didn't need, while topiramate aids in weight loss, if you can get a therapeutic dose.

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Anticonvulsants -- Some antiseizure drugs help prevent migraines, although researchers are not sure why: Divalproex sodium (Depakote); Gabapentin (Neurontin); Topiramate (Topamax).

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